Haki and Devil Fruits are two of the main sources of power for the many formidable villains in One Piece. Those who have both gain a huge advantage and are obviously stronger, with the likes of Kaido and Donquixote Doflamingo ruling the seas for years and driving Straw Hat Luffy to the brink of death.

One Piece: 5 Characters Who Can Beat God's Knight, Ranked
These One Pieces have the strength needed to take down the mighty God Knights.
Outside One Pieceshonen heroes like Naruto Uzumaki have more than enough power to compete with the series' strongest villains. At his peak, Naruto is capable of fighting god-like opponents. As the strongest shinobi in history, Naruto Uzumaki has more than enough strength to defeat these mighty One Piece villains.
8
Magellan
Devil Fruit: Doku Doku no Mi
In Impel Down lies a powerful villain who almost killed Luffy. That villain is Magellan, Impel Down's former head warden and the current user of Doku Doku no Mi, who can produce and manipulate various types of poisons or toxins at will. Aside from his toilet issues, Magellan is an absolute force of nature One Piece.
While Magellan's venom is extremely lethal and can kill most opponents within seconds of contact, Naruto Uzumaki is one of the worst possible enemies for this ability. With an overwhelmed healing factor, on top of his protective chakra cloaks, Naruto has what it takes to fight Magellan head on. On the contrary, Magellan would need much more than just poison to stand up to Naruto's overwhelming power.
7
Enel
Devil Fruit: Goro Goro no Mi
Enel is one of them One Piece villains best known for their extreme god complex. His arrogance is backed up by real power thanks to the Goro Goro no Mi, which gave him lightning-based abilities capable of knocking even the likes of Zoro and Sanji unconscious in one shot.
Enel ruled the Upper Yard and, for most of the Skypiea story, overpowered the combined might of the Straw Hat Pirates. Still, an opponent like Naruto Uzumaki, who possesses god-like abilities and has faced battles involving planetary-scale threats at his peak, would overwhelm him with ease.
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6
Donquixote Doflamingo
Devil Fruit: Ito Ito no Mi
Doffy, who fans love to call Doflamingo, is one of the most well-written villains who fought Luffy in One Piece. As such, Doflamingo has countless followers who are in awe of the warlord's Devil Fruit ability, Ito Ito no Mi, which gave him power and control over strings, be they invisible or parasitic. He is also a haki user, further adding to his formidable power.
Although it wouldn't be easy to outsmart Doflamingo, Naruto Uzumaki in Six Paths Sage Mode would have a clear advantage over him. Since Donquixote Doflamingo is very observant in battle, he would quickly realize that a fight with Naruto would be unfavorable. If he's already wary of what Fujitora can do when he summons a meteorite, fighting Naruto would be way beyond anything he could comfortably handle.
5
Greenbull
Devil Fruit: Mori Mori no Mi
Fasting is a way of life for Greenbull, the admiral who proclaims himself to be nature itself because of his devil fruit, Mori Mori no Mi. With his unique logia fruit, Greenbull can transform into a huge forest that can control all kinds of plants and vegetation to overwhelm his enemies. He is also capable of photosynthesis, which helps him recover his stamina and sustain his body without eating.
In a matchup with Naruto Uzumaki, Greenbull's constant regeneration would end up being an effective advantage. With hundreds of shadow clones firing Rasengan endlessly along with devastating Tailed Beast Balls, it would be difficult for Greenbull to withstand the cumulative damage of Naruto Uzumaki's attacks, let alone have time to recover.
4
Kizaru
Devil Fruit: Pika Pika no Mi
Logia Devil Fruit users like Admiral Kizaru are among the most troublesome opponents on the battlefield due to their intangibles. Only those with Haki can reliably bypass their defenses and damage them. Even worse, Kizaru's devil fruit, Pika Pika no Mi, grants him light-based abilities, including the power to turn into light at will.
To defeat Kizaru, Naruto Uzumaki would have to maintain relentless pressure with hundreds of shadow clones using the Rasenshuriken, which can cut opponents on a microscopic and cellular level. Kizaru's speed wouldn't be a problem for Naruto, who is already faster than the speed of light.
3
Big mom
Devil Fruit: Soru Soru no Mi
Fear is a natural human emotion that Big Mom's Devil Fruit, Soru Soru no Mi, weapons. Anyone who fears the former Emperor of the Sea risks losing their soul and being turned into a Homie that she can command at will.
Fortunately, Naruto Uzumaki is not easily intimidated, even in the presence of someone as overwhelming as Big Mom. After all, he is used to seeing Choji's technique in multiple sizes, not to mention Tailed Beasts in their physical form. Instead, Naruto would likely provoke Big Mom with a sharp comment before the fight really began.
Big Mom is among the rare fighters who can use all three types of Haki, yet Naruto Uzumaki in his Six Paths Sage Mode form operates on a higher scale of power. While it would be easy for Big Mom's Supreme King Haki to wipe out hundreds of ordinary shadow clones, eliminating eight shadow clones imbued with Tailed Beast power would be a different story.
2
Blackbeard
Devil Fruits: Gura Gura no Mi and Yami Yami no Mi
With two Devil Fruit powers in his possession, Gura Gura no Mi and Yami Yami no Mi, Blackbeard has established himself as one of the most dangerous and unpredictable villains in One Piecewith destructive potential and the daring ambition to one day rule the world.
However, in Naruto Uzumaki's presence, Blackbeard would still face serious problems, even with his ability to nullify the Devil Fruit. If chakra is treated as comparable to Devil Fruit powers, Naruto Uzumaki can still rely on pure taijutsu. In another scenario, Naruto was also able to overwhelm Blackbeard in a similar way to how he dealt with the Preta Path in the Pain Arc.
1
Kaido
Devil Fruit: Uo Uo no Mi Model: Seiryu
Few villains in One Piece are powerful enough to defeat Luffy, but Kaido proved to be able to overpower him more than once. As the overpowered captain of the Beasts Pirates and the fearsome tyrant Wano, Kaido is an extraordinary villain with extraordinary abilities. His Devil Fruit, the Uo Uo no Mi Model: Seiryu, transforms him into a fearsome Eastern Dragon that can use all three types of Haki.
Against Naruto Uzumaki, Kaido had no choice but to go all out. His stamina and durability would be pushed to their absolute limits, as Naruto Uzumaki in the Sage of Six Paths forms scales above him in overall power, speed and versatility. Most likely, even with Kurama Chakra Mode 2 combined with Sage Mode, Naruto Uzumaki would already have the upper hand against Kaido and be able to secure a win.
- Release date
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October 20, 1999
- Network
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Fuji TV
- Directors
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Hiroaki Miyamoto, Konosuke Uda, Junji Shimizu, Satoshi Itō, Munehisa Sakai, Katsumi Tokoro, Yutaka Nakajima, Yoshihiro Ueda, Kenichi Takeshita, Yoko Ikeda, Ryota Nakamura, Hiroyuki Kakudou, Takahiro Imamura, Toshihiro Ma Shihi Endo, Toshihiro Ma Shihi Endo, Kadota, Sumio Watanabe, Harume Kosaka, Yasuhiro Tanabe, Yukihiko Nakao, Keisuke Onishi, Junichi Fujise, Hiroyuki Satou
- Author
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Jin Tanaka, Akiko Inoue, Junki Takegami, Shinzo Fujita, Shouji Yonemura, Yoshiyuki Suga, Atsuhiro Tomioka, Hirohiko Uesaka, Michiru Shimada, Isao Murayama, Takuya Masumoto, Yoichi Takahashi, Momoka Toyoda
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Mayumi Tanaka
Monkey D. Luffy (voice)
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Kazuya Nakai
Roronoa Zoro (voice)