How to beat the radical rat boss in Mewgenics

Fans of Mewgenics must go through a series of battles in each chapter to progress through the acts and reach the end. Some levels feature mini-bosses with mobs attacking you in turn-based battles, while others are focused on the final boss; interestingly, each has its own dedicated theme song.

cat breeding mewgenics

Mewgenics Cat Breeding Guide

Here's how to breed your cats in Mewgenics and get the best units safely.

The Radical Rat Boss is the last boss you face in Act 1 Chapter 1, and it can be quite challenging if you don't know the right tactics. This guide describes how to easily defeat the Radical Rat Mewgenics.

All Radical Rat Boss stats and attacks

radical rat boss fight in mewgenics Image via GameRant; Source: Edmund McMillen, Tyler Glaiel

Radical Rat Boss Info

Statistics

HP

67

Speed

5

Happiness

5

As you might expect from the name, this boss is a giant rodent wearing cool sunglasses. Its special (and only) move is to launch Spawn Bombs onto the battlefield while keeping your distance.

radical rat boss throws spawn bombs in mewgenics Image via GameRant; Source: Edmund McMillen, Tyler Glaiel

These explosives are shaped like rat heads and target not only the tile they land on, but also 10 tiles horizontally and vertically (the gray exclamation point above them indicates the danger areas). Thankfully, they don't explode right away. Instead, they go off after your next hunting cat finishes its turnright after the boss attacks. All the tiles they hit burn, and stepping on them burns your cat.

How to beat the radical rat boss in Mewgenics

a cat defused the radical rat boss spawn bomb in mewgenics Image via GameRant; Source: Edmund McMillen, Tyler Glaiel

Beating the Radical Rat boss easily Mewgenicsyou must disarm the Spawn Bomb immediately after it is thrown. You can do this by crushing it with your cat's basic attack or any active or passive ability. It only has 1 HP, so even a small hit will work. The boss usually throws it near your units, so it's easy to target. Just don't delay or the arena will quickly be filled with deadly bombs.

a cat attacked the radical rat boss in mewgenics Image via GameRant; Source: Edmund McMillen, Tyler Glaiel

Once the bomb is defused, focus on attacking the Radical Rat.

That's basically the core strategy: hit the bomb first, then the boss.

Ranged units perform very well in this fight. Aside from the Hunter class (which is particularly strong against Radical Rat), any unit with a ranged attack or relevant passive can hit the boss from a safe distance. If you have items like the Puzzle Box or skills like Grab or Minihook that can pull Radical Rat towards you, use them strategically, especially near tank units or ones that deal melee damage.

Never place multiple cats in the same row or column. If the Spawn Bomb isn't disabled properly, it can deal fire damage to all of them at once.

Additionally, be sure to spend your Mana on healing yourself and nearby allies. You can also pick up food items from the ground for constant HP recovery, since your felines are likely to be damaged from previous mini-boss fights and you don't want them to die.

cats defeated the radical rat boss in mewgenics Image via GameRant; Source: Edmund McMillen, Tyler Glaiel

Before facing the Radical Rat boss, pick up traits that go with your cat's passive and consider using trinkets that can help in the fight (you'll lose them anyway if you fail the battle). Tracy's Adventure Store has some useful essentials, like antidotes for debuff removal, conductors for electrical damage if you have a compatible unit, and a Fanny Pack to increase food drops. However, the store's inventory is RNG-based, so availability may vary.


Mewgenics Tag Page Cover Art

System

PC-1


Released

February 10, 2026

Developer

Edmund McMillen, Tyler Glaiel

Publisher

Edmund McMillen, Tyler Glaiel

Number of players

Single player

Compatibility with Steam Deck

Unknown


Leave a Comment