All Mewgenics bosses in order (and their locations)

Edmund McMillen and Tyler Glaiel's Mewgenics is a pure nostalgia bomb, rightfully following the legacy of these popular indie creators. A large part of this roguelike is encountering a variety of enemies, and since the game consists of several acts, players will naturally want to know all the small and large enemies they will encounter. For that reason, this guide explains all the bosses in the Mewgenicsincluding secrets, intruders and event exclusive mobs.

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Mewgenics Boss Guide

Mewgenics follows a unique structure when it comes to categorizing managers. In particular, you will find five main types of these monsters in this game:

General Threats: Each act has a number of creatures, such as Kittens, Flies, Cat Caller, etc., that you have to fight in different stages to progress.
Mini Bosses: These are slightly more difficult encounters, normally around four in the first zone, with fewer appearing as you advance to new arenas.
Final Bosses: Each chapter i Mewgenics has a couple of final bosses (usually one), so you can meet about seven to eight of them in an entire act.
House bosses: These invade your home on their own after you clear certain areas.
Special Managers: Certain events along the way allow you to fight these rare mobs.

All Act 1 bosses in Mewgenics

Chapter	Mini Boss	Final Boss
The alley	Lucy Magnus Fenrir Maisie Arthur (Special)	Radical rat (easy way) Queen Hippo (Hard Path)
The drains	The flush master The Rat King	Boris
The junkyard	Can Creeper Trampy	Chubs & Nubs
The caves	Big Slime	A baby spider
The bone garden	Mother Maggot	Dybbuk
The Throbbing Domain (Secret)	No	Throbbing King

The Throbbing Domain can only be accessed via The Boneyard map after you defeat all versions of the Act 1 house boss. To make it easier, you can check out our complete guide here.

Others from team 1

House boss	Place
Guillotine	This giant cat is coming show up at your hut to eat your cats seven days after you finish chapter three, both included The caves and The bone garden.
Guillotine 2	She's basically Guillotina in a different form, and she appears seven mornings after you kill the house boss.
Guillotine 3	This most terrifying version of Guillotina raids your property several days later, after her previous form is defeated.

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Want to get the most out of your cats and every run in Mewgenics? Check out our tips and tricks to help you through this scary cat adventure.

All Act 2 Bosses in Mewgenics

Mewgenics strategy that lets you win automatically

Chapter	Mini Boss	Final Boss
The desert	Tire Gein Morana Marshmallow Arthur (Special) Dust Devil (Special)	Gambit (easy path) Zodiac (Hard Road)
The crater	Infected couple Rocky Bobo	Crater Maker
The bunker	Bumblebee's foot Lenny	Johnny
The moon	The abandoned	The man in the moon
The core	Cerberus	The Coven
The Rift (Secret)	No	CHAOS Soahc

Others from act 2

House boss	Place
Pyrophina	Since she's also a house boss like Guillotina, you'll be able to deal with her from your seat seven days after the crush The core.
Zaratana	This second home boss is an asteroid-like turtle, and you can 1v1 the seven mornings once The moon is ready.
Pyrophina vs Zaratana	Once you crush Zaratana, the next house boss fight (Pyrophina vs. Zaratana) will open up for you about seven days later in the game.

Who is that character?

Identify the silhouettes before time runs out.

Who is that character?

Identify the silhouettes before time runs out.

Easy (7.5s) Medium (5.0s) Hard (2.5s) Permadeath (2.5s)

All bosses in Act 3 of Mewgenics

Chapter	Mini Boss	Final Boss
The lab	Alice Chan Hung The drive Franklin Arthur (Special)	Speer Stacy
ice age	Bits of frost Rocksnows	Lord Bunga
The future	Dr. Missing Zaphauser	Hitler II
Jurassic	Dino lover	Dreadnoughts
The end	The swelling	Modern
The Infinite (The Secret)	No	The creator

Others from Act 3

House boss	Place
C-800	Armed with a shotgun, this terminator cat is tough to deal with. It may appear after you finish The Future/The End.
C-1000	As with C-800, this is the second home boss, available for 1v1 once The Future/The End is included.
Hitler III	You must solve the Act 3 puzzle before the last house boss can raid your home.