The world of Naruto has seen the introduction of quite a few rogue ninjas over the years. In fact, you could say that the concept of villain ninjas is one of the most exciting aspects of the series, as they create very exciting villains. When it comes to the strongest of rogue ninjas, it's no surprise to fans to know that the vast majority of them hail from Konoha.
In fact, Konoha has had the strongest shinobi ever since the concept of Shinobi villages came into existence. Of course, they would have the most powerful missing ninjas as well, and over the years Kishimoto has illustrated quite a few of them brilliantly.
Mizuki
When it comes to rogue ninjas, Mizuki is definitely the weakest of the lot from Konoha. Technically, Mizuki is just a non-canon villain ninja. In the anime, he ends up focused on quite a lot after the skirmish he has Naruto. He ends up turning into a rogue ninja and his life is turned upside down because of these events. He's not very good at anything, and even though he's endowed with external powers, Mizuki falls to a pathetic fate.
Orochimaru
Orochimaru is one of the most violent rogue ninjas fans have seen in Naruto series. At one point he was a loyal ninja of Konoha, but his curiosity got the better of him and he eventually conducted live experiments on humans.
When Hiruzen failed to pursue him for his actions, he fled the village and from there became a rogue ninja. He plays the role of a primary antagonist for a fairly significant part of the series, and until the very end he was a very important character.
Kabuto Yakushi
Kabuto Yakushi was once a member of Konoha as well. He was taken in by an orphanage in Konoha and then sent into the ANBU, where he went on several missions for the village. He eventually teamed up with Orochimaru, who sort of manipulated him as well.
He then became a loyal follower of Orochimaru and followed him all the way to the Hidden Sound Village. After Orochimaru's death, he became one of the main antagonists of the series, having absorbed almost all the power he could find. It took two powerful Uchiha in Itachi and Sasuke to match him.
Itachi Uchiha
Itachi Uchiha is one of Konoha's most powerful ninjas. He was a prodigy of the Uchiha clan. But he was forced to live his life in exile after his massacre of the Uchiha. Of course, this was on Danzo's orders. However, Itachi had to pay for what he did as well. He infiltrated the Akatsuki for Konoha and stopped them from attacking the Hidden Leaf Village as well.
Technically, Itachi was still a good guy, but he had to put up a facade, all for his village, and more importantly, his brother.
Obito Uchiha
Obito Uchiha was a brilliant shinobi and truly a force to be reckoned with in the Naruto series. Although Obito once wanted to become Hokage, the cruel twist of fate dealt him in the Third Great Ninja War saw him follow in Madara's footsteps. He was manipulated in a way where he decided the way forward was to embrace the Eye of Moon plan and that's exactly what he did.
Obito became a missing-nin and he led the Akatsuki from within the shadows. He was primarily responsible for the Fourth Great Ninja War and countless people died because of him.
Madara Uchiha
When it comes to strength, Madara Uchiha is truly one of the strongest of the rogue ninjas. Technically, Madara was the one responsible for creating Konoha, along with Hashirama.
However, realizing that the influence of Tobirama would become a problem for him, Madara's faith in Hashirama wavered and he decided to leave the village for good. Madara became a missing ninja and even attacked Konoha in an attempt to destroy it. This led to a battle between Hashirama and Madara in the Valley of the End, which the former eventually won. However, Madara's plans did not end there and he showed the fans why he was the greatest villain in the entire series.
Sasuke Uchiha
When it comes to the strongest of the rogue ninjas, Sasuke certainly tops the list. Sasuke is one of the strongest characters to have lived in the Naruto world. He left Konoha after meeting Itachi in a quest for more power. He then went on to train with Orochimaru. At this point he had not committed any crimes.
But the more Sasuke gained powers, the more he sank into darkness. Eventually, after the events of the Kage Summit, he was labeled a criminal and a rogue ninja. Sasuke helped defeat Akatsuki in the Ninja Wars, and he was pardoned for what he did to save the world.
